Paediatric methylphenidate (Ritalin®) restrictive conditions of prescription in France

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منابع مشابه

Ritalin (methylphenidate): clinical experiences.

METHYLPHENIDATE is a white, water-soluble crystalline compound. It is a piperidine derivative which can be administered orally, subcutaneously, intramuscularly or intravenously and is marketed under the name of "Ritalin" by Ciba Pharmaceuticals. It is a behaviour-alteirmg drug which is often included in the classification of tranquillizer or ataractic compounds (9). In contradistinction to the ...

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Methylphenidate (Ritalin)-associated cataract and glaucoma.

Methylphenidate hydrochloride (Ritalin) is the drug of choice for attention deficit hyperactivity disorder (ADHD). However, an association of Ritalin with glaucoma has been reported. We report a case of Ritalin-associated cataract and glaucoma. A 10-year-old boy was diagnosed with ADHD and had received methylphenidate hydrochloride, 60 mg/day for 2 years. He presented with blurred vision. Best-...

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Effects of methylphenidate (Ritalin) on selective attention in hyperactive children.

This study investigated the effect of methylphenidate (Ritalin) on the selective attention of hyperactive children designated as favorable or adverse responders to stimulant medication. Using a type II incidental learning paradigm, it was found that children in the drug condition recalled more central and less incidental stimuli than those children in the placebo condition. While no differentia...

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Liquid-chromatographic analysis for methylphenidate (Ritalin) in serum.

We describe a "high performance" liquid chromatographic method for quantitating methylphenidate in serum. The internal standard, 4,5-diphenylimidazole, and serum or plasma sample are extracted in chloroform, evaporated, and redissolved in 20 mmol/L potassium phosphate (pH 3.5)/high-purity acetonitrile, 80/20 by vol. A centrifuged aliquot is chromatographed on mu-Bondapak C-18 with the phosphat...

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Effects of methylphenidate (Ritalin) on mammalian myocardial ultrastructure.

Previous observations have indicated lamellated ultrastructural lesions in the myocardium of a patient treated with methylphenidate (Ritalin) hydrochloride (MPH). A causal relationship between MPH exposure and these membranous changes was tested in the myocardium of rats and mice. Following injection of varying doses of MPH for different periods, myocardial ultrastructure was examined and lesio...

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 2003

ISSN: 0306-5251,1365-2125

DOI: 10.1046/j.1365-2125.2003.01943.x